FIGURE

Fig. 5

ID

ZDB-FIG-090428-5

Publication

Faro et al., 2009 - T-Cell Factor 4 (tcf7l2) Is the Main Effector of Wnt Signaling During Zebrafish Intestine Organogenesis

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Fig. 5

Compound embryos apc^mcr/mcr; tcf4^exI/exI display the apc mutant cardiac phenotype. Dorsal view of 48 hpf wild-type (A), apc^mcr/mcr (B), and apc^mcr/mcr;tcf4^exI/exI (C) siblings after WISH for bmp4. Survival of apc tcf4 genotypes at 96 hpf (D). The depletion of Tcf4 in apc^mcr/mcr genetic background (gray bars) does not improve the survival of the apc mutant embryos. Values are mean ± standard error of mean; n>25 embryos per category; experiment was triplicated.

Expression Data

Gene:	bmp4
Fish:	WT apc^hu745/hu745 apc^hu745/hu745; tcf7l2^zf55/zf55
Anatomical Term:	myocardium
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	apc^hu745/hu745 tcf7l2^zf55/+ apc^hu745/+; tcf7l2^zf55/+ apc^hu745/+; tcf7l2^zf55/zf55 apc^hu745/hu745; tcf7l2^zf55/+ apc^hu745/hu745; tcf7l2^zf55/zf55
Observed In:	atrioventricular valve heart heart contraction whole organism
Stage Range:	Long-pec to Day 4

Phenotype Detail

Acknowledgments

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