FIGURE

Fig. 4

ID

ZDB-FIG-090428-4

Publication

Faro et al., 2009 - T-Cell Factor 4 (tcf7l2) Is the Main Effector of Wnt Signaling During Zebrafish Intestine Organogenesis

Other Figures

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Fig. 4

Tcf4 depletion in apc^mcr/mcr background rescues the expression of i-fabp, but not trypsin or l-fabp. Dorsal view of 72 hpf apc^mcr/mcr (A, C, E) and apc^mcr/mcr;tcf4^exI/exI (B, D, F) siblings after WISH for i-fabp (A, B), trypsin (C, D), and l-fabp (E, F). Histological analysis of transversal sections from the foregut of 80 hpf apc^mcr/mcr (G) and apc^mcr/mcr;tcf4^exI/exI (H) larvae stained with hematoxylin and eosin. Apc mutant embryos fail to develop properly polarized enterocytes, whereas in the double-mutant embryos this defect is rescued.

Expression Data

Genes:	fabp2 fabp10a prss1
Fish:	apc^hu745/hu745 apc^hu745/hu745; tcf7l2^zf55/zf55
Anatomical Terms:	enterocyte exocrine pancreas
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	apc^hu745/hu745 apc^hu745/hu745; tcf7l2^zf55/zf55
Observed In:	endodermal digestive tract morphogenesis exocrine pancreas development hepatocyte differentiation
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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