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Fig. 5 Compound embryos apcmcr/mcr; tcf4exI/exI display the apc mutant cardiac phenotype. Dorsal view of 48 hpf wild-type (A), apcmcr/mcr (B), and apcmcr/mcr;tcf4exI/exI (C) siblings after WISH for bmp4. Survival of apc tcf4 genotypes at 96 hpf (D). The depletion of Tcf4 in apcmcr/mcr genetic background (gray bars) does not improve the survival of the apc mutant embryos. Values are mean ± standard error of mean; n>25 embryos per category; experiment was triplicated.
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