FIGURE

Fig. S3

ID

ZDB-FIG-080502-15

Publication

Sanek et al., 2008 - A novel role for zebrafish zic2a during forebrain development

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Fig. S3

Forebrain patterning in zic2a morphants. (A, B) foxg1 expression in the telencephalon is not affected in zic2a morphants. (C, D) eomesa expression is normal in the telencephalon, but is reduced in anterior diencephalon (dashed red lines demarcate border between telencephalon and diencephalon). (E, F) lef1 expression is reduced in the PT region of Zic2a depleted embryos. (G, H) rx3 expression is not affected in the anterior hypothalamus, however (I, J) titf1a is weakly expanded anteriorly. (K, L) lhx1a expression is not affected in zic2a morphants at 2 dpf. Embryos are shown in lateral views, anterior to the left. All numbers for these experiments can be found in Supplementary Table 1.

Expression Data

Genes:	eomesa foxg1a lef1 lhx1a nkx2.4b rx3
Fish:	AB AB + MO3-zic2a
Knockdown Reagent:	MO3-zic2a
Anatomical Terms:	diencephalon hypothalamus preoptic area telencephalon ventral thalamus
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO3-zic2a
Knockdown Reagent:	MO3-zic2a
Observed In:	ventral thalamus
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 317(1), Sanek, N.A., and Grinblat, Y., A novel role for zebrafish zic2a during forebrain development, 325-335, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.