FIGURE

Fig. 3

ID

ZDB-FIG-080430-4

Publication

Jopling et al., 2007 - Shp2 Knockdown and Noonan/LEOPARD Mutant Shp2-Induced Gastrulation Defects

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Fig. 3

Shp2 Knockdown Did Not Affect Cell Specification
Control and Shp2-MO–injected embryos were fixed at 6 hpf (A–H, Q–X), 8 hpf (O,P), or 10 hpf (I–L), and in situ hybridization was done with the indicated probes. Either lateral views (A–D, Il–Ll, M, N, S, T, W, X) or animal pole views (E–H, Ia-La, O–R, U, V) are depicted here.

Expression Data

Genes:	bmp2b chrd egr2b fyna gsc ndr2 pax2a six3b tbxta wnt5b wnt11f2 yes1
Fish:	WT WT + MO2-ptpn11a
Knockdown Reagent:	MO2-ptpn11a
Anatomical Terms:	axial hypoblast forebrain neural keel margin midbrain hindbrain boundary neural keel presumptive rhombomere 3 presumptive rhombomere 5 shield whole organism
Stage Range:	Shield to Bud

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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