FIGURE

Fig. 5

ID

ZDB-FIG-071005-47

Publication

Walshe et al., 2003 - Fgf signalling is required for formation of cartilage in the head

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Fig. 5

Fgf3 is required for formation of ceratobranchial cartilages. (A–D) Ventral views showing loss of cartilage derivatives of pharyngeal arches 3-6 in 5-dpf embryos following inhibition of Fgf3. (A) Embryo injected with control morpholino. (B) Embryo injected with low concentration of Fgf3mo shows reduction in ceratobranchial cartilages derived from arches 3-6 (arrows). (C, D) Low and high magnification images of an embryo injected with a higher concentration of Fgf3mo. There is a complete absence of all ceratobranchial cartilage derivatives of arches 3–6. Hypobranchial and basibranchial elements are also missing, although a small midline cartilage nodule is present (arrow in T). However, the tooth-bearing ceratobranchial element derived from arch 7 is unaffected (arrowheads in B–D).

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Acknowledgments

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Reprinted from Developmental Biology, 264(2), Walshe, J. and Mason, I., Fgf signalling is required for formation of cartilage in the head, 522-536, Copyright (2003) with permission from Elsevier. Full text @ Dev. Biol.