Fig. 5

Fig. 5 Fgf3 is required for formation of ceratobranchial cartilages. (A–D) Ventral views showing loss of cartilage derivatives of pharyngeal arches 3-6 in 5-dpf embryos following inhibition of Fgf3. (A) Embryo injected with control morpholino. (B) Embryo injected with low concentration of Fgf3mo shows reduction in ceratobranchial cartilages derived from arches 3-6 (arrows). (C, D) Low and high magnification images of an embryo injected with a higher concentration of Fgf3mo. There is a complete absence of all ceratobranchial cartilage derivatives of arches 3–6. Hypobranchial and basibranchial elements are also missing, although a small midline cartilage nodule is present (arrow in T). However, the tooth-bearing ceratobranchial element derived from arch 7 is unaffected (arrowheads in B–D).