FIGURE

Fig. 2

ID

ZDB-FIG-051108-1

Publication

Walshe et al., 2003 - Fgf signalling is required for formation of cartilage in the head

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Fig. 2

Migrating neural crest cells are recipients of Fgf signals. (A, B) Dorsal (A) and lateral (B) views of 24-hpf embryos showing expression of Dlx2 to show the locations of the three pharyngeal neural crest streams (numbered). (C, D) Dorsal (C) and lateral (D) views of 24-hpf embryos showing expression of Erm in the second and third neural crest streams but little expression in the first stream that migrates adjacent to the isthmus. Transcripts are also detected in the neural tube associated with the isthmus (i) and are detected more weakly in rhombomere boundaries in (C). (E, F) Treatment of embryos with 100 μM SU5402 between 18 and 24 hpf: Dlx2 expression shows that all three neural crest streams are still present (E) but Erm is undetectable (F). Arrowheads in (A) and (C) indicate the position of the first pharyngeal pouch.

Expression Data

Genes:	dlx2a etv5b
Fish:	WT
Condition:	chemical treatment: SU5402
Anatomical Terms:	mandibular arch skeleton midbrain hindbrain boundary pharyngeal arch 2 skeleton pharyngeal arch 3 skeleton
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 264(2), Walshe, J. and Mason, I., Fgf signalling is required for formation of cartilage in the head, 522-536, Copyright (2003) with permission from Elsevier. Full text @ Dev. Biol.