FIGURE

Fig. 1

ID

ZDB-FIG-060620-12

Publication

Alt et al., 2006 - Analysis of origin and growth of the thyroid gland in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Differentiation markers start to be expressed in the thyroid primordium during embryonic development in zebrafish. A: Simplified sketch depicting the physiological activity of a vertebrate thyroid follicle cell (blue, nucleus light blue). The red arrow indicates that Ctsb is also required for human thyroglobulin (TG) degradation after endocytosis. Note that the gene slc5a5 encodes the sodium/iodide symporter NIS. For further details, see text. B-K: Expression of thyroid markers in zebrafish embryos. Whole-mounts (B-G) and sections (H-K); lateral views (B,C,F,G) and ventral views (D,E), anterior always to the left. The stage is shown bottom right, the probe/staining bottom left. B-I: Wild-type embryos; J,K: cross-sections of noi^tu29 homozygous embryos. Arrows point to the thyroid primordium, asterisks mark pharyngeal mesenchyme, and arrowheads expression of ctsb in the yolk syncytial layer. hy, hypothalamus; J^-, iodide; TPO, thyroperoxidase.

Expression Data

Genes:	ctsba nkx2.4b slc5a5 tg
Fish:	WT pax2a^tu29a/tu29a
Anatomical Terms:	hypothalamus pharyngeal arch thyroid follicle thyroid primordium whole organism yolk syncytial layer
Stage Range:	Prim-5 to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.