Gene
ctsba
- ID
- ZDB-GENE-040426-2650
- Name
- cathepsin Ba
- Symbol
- ctsba Nomenclature History
- Previous Names
-
- ctsb
- id:ibd1201
- wu:fa13g05
- wu:fb34e12
- zgc:55862
- zgc:65809
- zgc:77181 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have cysteine-type endopeptidase activity. Involved in dorsal/ventral pattern formation; fin regeneration; and morphogenesis of an epithelium. Predicted to localize to extracellular space and lysosome. Human ortholog(s) of this gene implicated in diabetes mellitus. Is expressed in several structures, including blastoderm cell; endocrine system; macrophage; midbrain hindbrain boundary; and yolk. Orthologous to human CTSB (cathepsin B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65809 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Langdon et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Keratolytic winter erythema | 148370 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR000169 | Cysteine peptidase, cysteine active site |
| Active_site | IPR025660 | Cysteine peptidase, histidine active site |
| Active_site | IPR025661 | Cysteine peptidase, asparagine active site |
| Domain | IPR000668 | Peptidase C1A, papain C-terminal |
| Domain | IPR012599 | Peptidase C1A, propeptide |
| Family | IPR013128 | Peptidase C1A |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Length | Cysteine peptidase, asparagine active site | Cysteine peptidase, cysteine active site | Cysteine peptidase, histidine active site | Papain-like cysteine peptidase superfamily | Peptidase C1A | Peptidase C1A, papain C-terminal | Peptidase C1A, propeptide |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6PH75
|
330 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ctsba-201
(1)
|
Ensembl | 1,429 nt | ||
| mRNA |
ctsba-208
(1)
|
Ensembl | 920 nt | ||
| ncRNA |
ctsba-002
(1)
|
Ensembl | 777 nt | ||
| ncRNA |
ctsba-003
(1)
|
Ensembl | 939 nt | ||
| ncRNA |
ctsba-004
(1)
|
Ensembl | 778 nt | ||
| ncRNA |
ctsba-005
(1)
|
Ensembl | 796 nt | ||
| ncRNA |
ctsba-007
(1)
|
Ensembl | 562 nt | ||
| ncRNA |
ctsba-008
(1)
|
Ensembl | 619 nt | ||
| ncRNA |
ctsba-009
(1)
|
Ensembl | 848 nt | ||
| ncRNA |
ctsba-010
(1)
|
Ensembl | 563 nt |
Interactions and Pathways
No data available
Plasmids
No data available