FIGURE

Fig. 4

ID

ZDB-FIG-060601-5

Publication

Davidson et al., 2006 - The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis

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Fig. 4

Erythropoiesis in cdx-deficient embryos. (A) Whole mount in situ hybridizations showing gata1 transcripts (purple) in cdx-deficient embryos and wild-type controls at the 5-, 10- and 18-somite stages (flatmounted embryos shown in dorsal views of the trunk with anterior to the left) and at 24 hpf (shown in lateral views with anterior to the left). (B) Bar graph showing the number of gata1-expressing cells in cdx-deficient and wild-type embryos at the 5-, 10-, and 18-somite stages. Values represent mean (indicated above each bar) ± SD (n = 4). *Significant difference P < 0.01; **Significant difference P < 0.001 compared to wild-type controls.

Expression Data

Gene:	gata1a
Fish:	WT cdx4^{tv205c/tv205c} WT + MO2-cdx1a cdx4^{tv205c/tv205c} + MO2-cdx1a
Knockdown Reagent:	MO2-cdx1a
Anatomical Terms:	intermediate cell mass of mesoderm posterior lateral mesoderm
Stage Range:	5-9 somites to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 292(2), Davidson, A.J., and Zon, L.I., The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis, 506-518, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.