- Title
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Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis
- Authors
- Wang, J., Thomas, H.R., Li, Z., Yeo, N.C.F., Scott, H.E., Dang, N., Hossain, M.I., Andrabi, S.A., Parant, J.M.
- Source
- Full text @ Cell Death Dis.
24 hpf zebrafish embryos were treated with |
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EXPRESSION / LABELING:
PHENOTYPE:
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PHENOTYPE:
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Percentage of phenotypic apoptotic categories in wild type, tp63?/?, sibling tp63+/?, and sibling tp63+/+ zebrafish embryos at 4?h after treatment with DMSO or PMA. B Percentage of phenotypic categories in 24 hpf wild type and tp53?/? tp73?/? zebrafish embryos at 4?h after DMSO or PMA treatment. n?=?6 (A) and n?=?5 (B) from pooled embryos per sample. The total number of Thaps treated embryos: wild type?>?600, tp63?/??>?140, tp63+/??>?390, tp63+/+?>?180, and tp53?/? tp73?/??>?370. Bars represent mean?±?SEM. ****p?0.0001. |