TALEN

TALEN2-vegfaa

ID

ZDB-TALEN-180411-1

Name

TALEN2-vegfaa

Previous Names

None

Target

vegfaa (1)

Target Sequence 1

5' - TATTTGATACAGTTAT - 3'

Target Sequence 2

5' - ACAGCAGACAGATGGAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf1090	vegfaa
zf1091	vegfaa

Expression

Gene expression in Wild Types + TALEN2-vegfaa

No data available

Phenotype

Phenotype resulting from TALEN2-vegfaa

No data available

Phenotype of all Fish created by or utilizing TALEN2-vegfaa

Phenotype	Fish	Conditions	Figures
heart structure, abnormal	vegfaa^{zf1090/zf1090}	control	Fig. 4 from Zhu et al., 2017
ventricular myocardium bmp4 expression mislocalised, abnormal	vegfaa^{zf1090/zf1090}	control	Fig. 4 from Zhu et al., 2017
heart increased length, abnormal	vegfaa^{zf1090/zf1090}	control	Fig. 4 from Zhu et al., 2017
heart linear, abnormal	vegfaa^{zf1090/zf1090}	control	Fig. 4 from Zhu et al., 2017
cardioblast migration to the midline involved in heart field formation delayed, abnormal	vegfaa^{zf1090/zf1090}	control	Fig. 3 from Zhu et al., 2017
heart decreased width, abnormal	vegfaa^{zf1090/zf1090}	control	Fig. 4 from Zhu et al., 2017
heart hypotrophic, abnormal	vegfaa^{zf1090/zf1090}	control	Fig. 4 from Zhu et al., 2017
presumptive cardiac ventricle primitive heart tube cardioblast migration to the midline involved in heart field formation delayed, abnormal	vegfaa^{zf1090/zf1090}	control	Fig. 3 from Zhu et al., 2017
heart looping process quality, abnormal	vegfaa^{zf1090/zf1090}	control	Fig. 4 from Zhu et al., 2017
whole organism anterior-posterior axis decreased length, abnormal	vegfaa^{zf1090/zf1090} (AB)	standard conditions	Fig. 1 from Jin et al., 2017
axial blood vessel efnb2a expression absent, abnormal	vegfaa^{zf1090/zf1090} (AB)	standard conditions	Fig. 2 from Jin et al., 2017
axial blood vessel dab2 expression increased distribution, abnormal	vegfaa^{zf1090/zf1090} (AB)	standard conditions	Fig. 2 from Jin et al., 2017
axial blood vessel hey2 expression absent, abnormal	vegfaa^{zf1090/zf1090} (AB)	standard conditions	Fig. 2 from Jin et al., 2017
pericardium edematous, abnormal	vegfaa^{zf1090/zf1090} (AB)	standard conditions	Fig. 1 from Jin et al., 2017
blood circulation disrupted, abnormal	vegfaa^{zf1090/zf1090} (AB)	standard conditions	Fig. 1 from Jin et al., 2017
heart cardiac muscle cell decreased amount, abnormal	vegfaa^{zf1090/zf1090}; f2Tg	control	Fig. 5 from Zhu et al., 2017
cardiac ventricle cardiac muscle cell decreased amount, abnormal	vegfaa^{zf1090/zf1090}; f2Tg	control	Fig. 5 from Zhu et al., 2017
heart tube formation decreased occurrence, abnormal	vegfaa^{zf1090/zf1090}; la116Tg; sd7Tg	control	Fig. 1 from Zhu et al., 2017
cardiac ventricle hypotrophic, abnormal	vegfaa^{zf1090/zf1090}; la116Tg; sd7Tg	control	Fig. 1 from Zhu et al., 2017
heart linear, abnormal	vegfaa^{zf1090/zf1090}; la116Tg; sd7Tg	control	Fig. 1 from Zhu et al., 2017
heart valve malformed, abnormal	vegfaa^{zf1090/zf1090}; la116Tg; sd7Tg	control	Fig. 1 from Zhu et al., 2017
endocardium endothelial cell accumulation heart anatomical space, abnormal	vegfaa^{zf1090/zf1090}; la116Tg; sd7Tg	control	Fig. 1 from Zhu et al., 2017
heart structure, abnormal	vegfaa^{zf1090/zf1090}; la116Tg; sd7Tg	control	Fig. 1 from Zhu et al., 2017
heart looping process quality, abnormal	vegfaa^{zf1090/zf1090}; la116Tg; sd7Tg	control	Fig. 1 from Zhu et al., 2017
atrium hypotrophic, abnormal	vegfaa^{zf1090/zf1090}; la116Tg; sd7Tg	control	Fig. 1 from Zhu et al., 2017
dorsal longitudinal anastomotic vessel absent, abnormal	vegfaa^{zf1090/zf1090}; s843Tg	standard conditions	Fig. 2 from Jin et al., 2017
posterior cardinal vein blood vessel endothelial cell increased amount, abnormal	vegfaa^{zf1090/zf1090}; s843Tg	standard conditions	Fig. 3 from Jin et al., 2017
dorsal aorta blood vessel endothelial cell absent, abnormal	vegfaa^{zf1090/zf1090}; s843Tg	standard conditions	Fig. 3 from Jin et al., 2017
dorsal aorta absent, abnormal	vegfaa^{zf1090/zf1090}; s843Tg	standard conditions	Fig. 2 from Jin et al., 2017
intersegmental vessel angiogenic sprout decreased length, abnormal	vegfaa^{zf1090/zf1090}; s843Tg	standard conditions	Fig. 4 from Jin et al., 2017
cerebellar central artery angiogenic sprout decreased amount, abnormal	vegfaa^{zf1090/zf1090}; s843Tg	standard conditions	Fig. 5 from Jin et al., 2017
metencephalic artery absent, abnormal	vegfaa^{zf1090/zf1090}; s843Tg	standard conditions	Fig. 6 from Jin et al., 2017
mesencephalic vein absent, abnormal	vegfaa^{zf1090/zf1090}; s843Tg	standard conditions	Fig. 6 from Jin et al., 2017
intersegmental vessel angiogenic sprout decreased amount, abnormal	vegfaa^{zf1090/zf1090}; s843Tg	standard conditions	Fig. 4 from Jin et al., 2017
cerebellar central artery decreased amount, abnormal	vegfaa^{zf1090/zf1090}; s843Tg	standard conditions	Fig. 5 from Jin et al., 2017
mesencephalic artery absent, abnormal	vegfaa^{zf1090/zf1090}; s843Tg	standard conditions	Fig. 5, Fig. 6 from Jin et al., 2017
cerebellar central artery angiogenic sprout decreased amount, abnormal	vegfaa^{zf1091/zf1091}; s843Tg	standard conditions	Fig. 5 from Jin et al., 2017
mesencephalic artery absent, abnormal	vegfaa^{zf1091/zf1091}; s843Tg	standard conditions	Fig. 5 from Jin et al., 2017
cerebellar central artery decreased amount, abnormal	vegfaa^{zf1091/zf1091}; s843Tg	standard conditions	Fig. 5 from Jin et al., 2017

Citations