Morpholino

MO1-ascl1b

ID

ZDB-MRPHLNO-050308-14

Name

MO1-ascl1b

Previous Names

Target

Sequence

5' - TCGTAGCGACGACAGTTGCCTCCAT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-ascl1b

Expressed Gene	Anatomy	Figures
dla	hindbrain	Fig. S6 from Nikolaou et al., 2009
foxb1a	hindbrain	Fig. 6 from Amoyel et al., 2005
gcga	pancreatic bud	Fig. 7 from Flasse et al., 2013
ghrl	pancreatic bud	Fig. 7 from Flasse et al., 2013
ins	pancreatic bud	Fig. 7 from Flasse et al., 2013
isl1a	pancreatic bud	Fig. 7 from Flasse et al., 2013
lfng	hindbrain	Fig. S6 from Nikolaou et al., 2009
neurod1	pancreas primordium trunk embryonic structure	Fig. 8 from Flasse et al., 2013
pkd2l1	cerebrospinal fluid contacting neuron	Fig. 3 from Di Bella et al., 2019
rfng	hindbrain	Fig. 6 from Amoyel et al., 2005
sox4b	pancreas primordium trunk embryonic structure	Fig. 8 from Flasse et al., 2013
sst2	pancreatic bud	Fig. 7 from Flasse et al., 2013

Phenotype

Phenotype resulting from MO1-ascl1b

Phenotype	Fish	Figures
cerebrospinal fluid contacting neuron pkd2l1 expression decreased amount, abnormal	WT + MO1-ascl1b	Fig. 3 from Di Bella et al., 2019
cerebrospinal fluid contacting neuron decreased amount, abnormal	WT + MO1-ascl1b	Fig. 3 from Di Bella et al., 2019

Phenotype of all Fish created by or utilizing MO1-ascl1b

Phenotype	Fish	Conditions	Figures
cerebrospinal fluid contacting neuron decreased amount, abnormal	WT + MO1-ascl1b	standard conditions	Fig. 3 from Di Bella et al., 2019
cerebrospinal fluid contacting neuron pkd2l1 expression decreased amount, abnormal	WT + MO1-ascl1b	standard conditions	Fig. 3 from Di Bella et al., 2019
cerebrospinal fluid contacting neuron pkd2l1 expression decreased amount, abnormal	ascl1a^{t25215/t25215} + MO1-ascl1b	standard conditions	Fig. 3 from Di Bella et al., 2019
cerebrospinal fluid contacting neuron decreased amount, exacerbated	ascl1a^{t25215/t25215} + MO1-ascl1b	standard conditions	Fig. 3 from Di Bella et al., 2019
cell proliferation in hindbrain disrupted, abnormal	WT + MO1-ascl1b + MO3-ascl1a	standard conditions	Fig. 4 from Amoyel et al., 2005
neurogenesis disrupted, abnormal	WT + MO1-ascl1b + MO3-ascl1a	standard conditions	Fig. 4 from Amoyel et al., 2005
hindbrain decreased width, abnormal	WT + MO1-ascl1b + MO3-ascl1a	standard conditions	Fig. 4 from Amoyel et al., 2005
hindbrain morphogenesis delayed, abnormal	WT + MO1-ascl1b + MO3-ascl1a	standard conditions	Fig. 4 from Amoyel et al., 2005
endocrine pancreas development disrupted, abnormal	WT + MO1-ascl1b + MO3-neurod1	standard conditions	Fig. 9 , Fig. 10 from Flasse et al., 2013

Citations