Gene
lfng
- ID
- ZDB-GENE-980605-16
- Name
- LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- Symbol
- lfng Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity. Acts upstream of or within fin regeneration; hypochord development; and negative regulation of neuron differentiation. Predicted to be located in Golgi membrane. Is expressed in several structures, including blastodisc; central nervous system; germ ring; neural plate; and sensory system. Human ortholog(s) of this gene implicated in spondylocostal dysostosis 3. Orthologous to human LFNG (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 28 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55213 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Nikolaou et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spondylocostal dysostosis 3 | Alliance | Spondylocostal dysostosis 3, autosomal recessive | 609813 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Fringe | Fringe-like, glycosyltransferase domain |
|---|---|---|---|
|
UniProtKB:B2GQK5
|
374 | ||
|
UniProtKB:Q8JHF2
|
374 |
Interactions and Pathways
No data available
Plasmids
No data available