ZFIN Image: Han et al., 2014, Fig. 8

Image

Figure Caption

Fig. 8

Morphants of p75, TROY, and Nogo-C2/NgRH1a with malformed PLL primordium exhibit decreased expression of downstream markers of Fgf signaling.

Whole-mount in situ hybridization was performed with probes against markers of PLL primordium organization in control embryo and the indicated morphants. The expression patterns of cxcr4b (A–D), cxcr7b (E–H), and lef1 (I–L) were similar in control embryo and morphants. Expression of downstream markers of Fgf signaling (pea3 (M–P), dkk1b (Q–T), and atoh1a (U–X)) were reduced in all morphants examined as compared to the control. (α–δ) The expression pattern of fgfr1a in the PLL primordium was no different between the control and the morphants. Scale bar, 20 μm.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One