FIGURE

Fig. 1

ID

ZDB-FIG-241126-10

Publication

Yu et al., 2024 - Aspirin reduces Ponatinib-induced cardiovascular toxic phenotypes and death in zebrafish

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Fig. 1

The effects of Ponatinib on the morphology of zebrafish larvae. (A) Survival curves of 1 dpf zebrafish larvae exposed to indicated concentrations of Ponatinib or 0.1 % DMSO (vehicle control) for 3 days (n=15). (B) Body length of 4 dpf zebrafish (n=7). Data are represented as mean � SEM. **P < 0.01 and ***P < 0.005 vs. control group. (C) Representative images of Ponatinib-induced pericardial edema in 4 dpf zebrafish. (D) The pericardial edema rate in 15 fish/group batches. Data are represented as mean � SEM. ***P < 0.005 vs. control group. (E) The pericardial edema area (n>15). Data are represented as mean � SEM. ***P < 0.005 vs. control group.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	chemical treatment by environment: ponatinib
Observed In:	pericardium whole organism
Stage Range:	Protruding-mouth to Day 4

Phenotype Detail

Acknowledgments

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