FIGURE

Fig. 4

ID

ZDB-FIG-240930-119

Publication

Shojaeinia et al., 2024 - Deoxyhypusine synthase deficiency syndrome zebrafish model: aberrant morphology, epileptiform activity, and reduced arborization of inhibitory interneurons

Other Figures

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Fig. 4

LFP recording of dhps knockdown larvae. (A) Snapshot of LFP signal recorded from 4-dpf Wt, Ctrl MO and dhps E2I2 MO larvae. (B) One-way ANOVA revealed that the frequency of ictal-like events in dhps knockdown larvae was significantly increased compared to control larvae (p ≤ 0.02). Each recording was performed over a period of 20 min. (C) Each pie chart shows percentage of larvae with more than 3 ictal-like events during 20 min of recording. While in Ctrl MO larvae less than 10% of larvae had more than 3 ictal-like events, in dhps E2I2 MO-injected larvae, more than 43% of larvae had more than 3 ictal-like events

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO3-dhps
Knockdown Reagent:	MO3-dhps
Observed In:	optic tectum action potential initiation
Stage:	Day 4

Phenotype Detail

Acknowledgments

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