FIGURE

Figure 8

ID

ZDB-FIG-240607-127

Publication

Fabian et al., 2024 - Comprehensive phenotypic characterization of an allelic series of zebrafish models of NEB-related nemaline myopathy

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Figure 8

Thin filaments are shorter neb mutants. (A) Linear regression graphs of thin filament lengths measured at 1.6–2.6 μm sarcomere lengths. Thin filament length was reduced in all neb mutants compared to wt siblings. (B) Graphs of thin filament lengths measured at 1.85–2.2 μm sarcomere length (mean ± SEM). Thin filament length was significantly reduced in all neb mutants. Asterisks indicate p-values (* ≤ 0.05; ** ≤ 0.01; *** ≤ 0.001; **** ≤ 0.0001). See Supplemental Table 6 for statistics.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	neb^{hu2849/hu2849} neb^{sa11973/sa11973} neb^{sa21475/sa21475} neb^{sa30646/sa30646} neb^{sa34628/sa34628}
Observed In:	skeletal muscle cell striated muscle thin filament
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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