FIGURE

Fig. 6

ID

ZDB-FIG-231106-63

Publication

Virtanen et al., 2023 - Effect of caldesmon mutations in the development of zebrafish embryos

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Fig. 6

Cald1 mutation has mild locomotory phenotype in zebrafish larvae Analyses of behavior and locomotion of cald1a and cald1b mutants in 96-well assay using DanioVision instrument. After the adaptation phase, an alternating light-dark cycles (5min light, 5min darkness) were used to stimulate movements. Some genotypes were pooled to increase statistical power. A) control (n = 52, genotypes wt; cald1a+/− and cald1b+/−) vs cald1a, cald1b double-mutants (n = 13, genotypes, cald1a−/−, cald1b−/−), B) control vs cald1a mutants (n = 24, genotypes cald1a−/− and cald1a−/−, cald1b+/−), C) control vs cald1b mutants (n = 38, genotypes cald1b−/− and cald1b−/−,cald1a+/−), D) Stimulation of wt (n = 5) or cald1a,cald1b mutants (n = 5) with pentylene tetrazolium (PTZ). In A-C the same control data are shown as reference.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT cald1a^{sa16974/sa16974} cald1b^{sa24667/sa24667} cald1a^{sa16974/sa16974}; cald1b^{sa24667/sa24667}
Conditions:	altered light dark cycle altered light dark cycle, chemical treatment by environment: pentetrazol
Observed In:	swimming behavior
Stage:	Day 4

Phenotype Detail

Acknowledgments

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