FIGURE

Fig. 3

ID

ZDB-FIG-230605-3

Publication

Wu et al., 2022 - Assessment of stromal SCD-induced drug resistance of PDAC using 3D-printed zPDX model chips

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Fig. 3

SCD expression characterizes CAF types and lipid metabolism

(A) PCA analysis of 9 primary CAFs depending on SCD expression level (RNA-seq).

(B) Correlation analysis of the CAFs’ transcriptomic profiles.

(D) Correlation analysis on SCD expression level and lipid genes (ELOVL5, HAC02, and ACSL4) on CAFs.

(E) Correlation analysis between SCD expression in CAFs and the C16 fatty acid monodesaturation ratios in the respective PDAC tissues.

(F) Correlation analysis between SCD expression in CAFs and the C18 fatty acid monodesaturation ratios in the respective PDAC tissues. p < 0.05 was considered significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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