ZFIN Image: Wu et al., 2022, Fig. 3

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Figure Caption

Fig. 3

SCD expression characterizes CAF types and lipid metabolism

(A) PCA analysis of 9 primary CAFs depending on SCD expression level (RNA-seq).

(B) Correlation analysis of the CAFs’ transcriptomic profiles.

(C) 538 DEGs identified among 12 paired primary SCD^low CAF and SCD^high CAF.

(D) Correlation analysis on SCD expression level and lipid genes (ELOVL5, HAC02, and ACSL4) on CAFs.

(E) Correlation analysis between SCD expression in CAFs and the C16 fatty acid monodesaturation ratios in the respective PDAC tissues.

(F) Correlation analysis between SCD expression in CAFs and the C18 fatty acid monodesaturation ratios in the respective PDAC tissues. p < 0.05 was considered significant.

Acknowledgments

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