FIGURE

Fig. 6

ID

ZDB-FIG-220304-50

Publication

Aman et al., 2021 - Thyroid hormone regulates abrupt skin morphogenesis during zebrafish postembryonic development

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Fig. 6

TH regulates densification of the primary hypodermis. (A) Primary hypodermal cells, visualized by imaging ET37:EGFP transgenic fish, have normal density in hypoTH individuals at 6.4 SSL. By 8.2 SSL, the primary hypodermis of hypoTH individuals appeared sparser than euTH controls. (B) Dermal cell density (cell/mm2) was similar in euTH and hypoTH fish at 6.4 SSL. By 8.2 mm SSL, euTH fish had significantly denser dermis than hypoTH siblings. Shared letters above groups indicate means not significantly different in post hoc Tukey Kramer comparisons (TH condition x stage interaction F1,10.4 = 109.1, p < 0.0001; mixed model ANOVA with individuals treated as random effect). Scale bar, (A) 100 μm.

Expression Data

Gene:	EGFP
Fish:	sqet37Et; wprt8Tg/+ sqet37Et; wprt8Tg/wprt8Tg
Anatomical Term:	hypodermal cell
Stage Range:	Days 7-13 to Days 14-20

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sqet37Et; wprt8Tg/+ sqet37Et; wprt8Tg/wprt8Tg
Observed In:	hypodermal cell integument integument hypodermal cell
Stage Range:	Prim-5 to Days 14-20

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 477, Aman, A.J., Kim, M., Saunders, L.M., Parichy, D.M., Thyroid hormone regulates abrupt skin morphogenesis during zebrafish postembryonic development, 205-218, Copyright (2021) with permission from Elsevier. Full text @ Dev. Biol.