FIGURE

Fig. 3

ID

ZDB-FIG-220211-10

Publication

Wohlfart et al., 2022 - Accumulation of acetaldehyde in aldh2.1^-/- zebrafish causes increased retinal angiogenesis and impaired glucose metabolism

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Fig. 3

Thickening of blood vessels and reduction of vascular mural cell coverage in aldh2.1^−/−retinae. A: Representative light microscopy images of zebrafish retinae prepared with trypsin digestion and hematoxylin staining. Red Arrow: erythrocyte, black arrow: pericyte, white arrow: endothelial cell, black scale bar: 100 μm. B-E: Quantification of vascular parameters. B: Increased vessel diameter, C: Increased capillary area, D: Unaltered endothelial cell count and E: Reduced vascular mural cell count. n = 37–39. Statistical analysis was done via Student's t-test, ns = not significant, *p < 0.05, ***p < 0.001. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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