FIGURE

Fig. s6

ID

ZDB-FIG-211105-25

Publication

Eom et al., 2021 - Immunoglobulin superfamily receptor junctional adhesion molecule 3 (Jam3) requirement for melanophore survival and patterning during formation of zebrafish stripes

Other Figures

All Figure Page

Back to All Figure Page

Fig. s6

jam3b dependent melanophore development in mutants of igsf11 and kita. (A) No-primary antiserum control staining jam3b:Jam3b-mCherry+ melanophore imaged identically to melanophore in Fig. 6A. (B) Fish heterozygous for igsf11^vp15rc4 or jam3b^vp8rc2 had pigment patterns with only occasional breaks in otherwise wild-type stripes (upper). Fish heterozygous for both mutations had numerous stripe breaks (middle) and fish homozygous for both mutations lacked hypodermal melanophores over the middle flank but often developed lightly melanized melanophores along the ventral margin of the flank (lower). (C) A population of regulative melanophores develops in homozygous kita mutants (upper), but these cells were entirely missing (middle), or further reduced in number (lower), by simultaneous homozygous mutation of jam3b or igsf11.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 476, Eom, D.S., Patterson, L.B., Bostic, R.R., Parichy, D.M., Immunoglobulin superfamily receptor junctional adhesion molecule 3 (Jam3) requirement for melanophore survival and patterning during formation of zebrafish stripes, 314-327, Copyright (2021) with permission from Elsevier. Full text @ Dev. Biol.