FIGURE

Figure 2

ID

ZDB-FIG-210902-264

Publication

Park et al., 2021 - Long-Chain Acyl-Carnitines Interfere with Mitochondrial ATP Production Leading to Cardiac Dysfunction in Zebrafish

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Figure 2

Experimental design of LCAC treatments in zebrafish embryos and survival rates for different concentrations of LCACs. Interrupted mitochondrial function by LCACs is accompanied by decreased ATP production. (A) Experimental design of compound treatments. (B) Lethality of the compounds at different concentrations. (C,D) Quantitative real-time PCR targeting genes related to ATP production (SD, n = 3, ns: p > 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001). (E,F) Assessment of relative ATP content in zebrafish embryos after compound treatments (SD, n = 3, ns: p > 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001). Abbreviations: rel. = relative, ns = not significant, wt = wild-type, SFA = sodium fluoroacetate.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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