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Figure 2

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ZDB-IMAGE-210902-264
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Figures for Park et al., 2021
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Figure Caption

Figure 2

Experimental design of LCAC treatments in zebrafish embryos and survival rates for different concentrations of LCACs. Interrupted mitochondrial function by LCACs is accompanied by decreased ATP production. (A) Experimental design of compound treatments. (B) Lethality of the compounds at different concentrations. (C,D) Quantitative real-time PCR targeting genes related to ATP production (SD, n = 3, ns: p > 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001). (E,F) Assessment of relative ATP content in zebrafish embryos after compound treatments (SD, n = 3, ns: p > 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001). Abbreviations: rel. = relative, ns = not significant, wt = wild-type, SFA = sodium fluoroacetate.

Acknowledgments
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