FIGURE

FIGURE 7

ID

ZDB-FIG-210718-27

Publication

Łysyganicz et al., 2021 - Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia

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FIGURE 7

Change in mutant behavior. (A) Tracks of swimming patterns of Wild type and Triple mutant fish treated and untreated with disorientating stimulus. Black lines correspond to slow swimming (<5 mm/s), green lines indicate medium speed (5–10 mm/s) and red lines indicate fast swimming (>10 mm/s). The figure shows a representative swimming pattern of one larvae. (B) Swimming distance normalized to swimming distance by non-treated wild types. (C) TAP952 stained cilia in cristae of treated and untreated fish. (D) Number of cilia in cristae (mean with 95% CI. T-test *p < 0.05). ns, no significant.

Expression Data

Antibody:	Ab2-tub-glyc
Fish:	WT hdac10^sh401/sh401; hdac6^sh400/sh400; sirt2^sh626/sh626
Condition:	mechanical stress
Anatomical Terms:	anterior crista kinocilium lateral crista kinocilium posterior crista kinocilium
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT hdac10^sh401/sh401; hdac6^sh400/sh400; sirt2^sh626/sh626
Condition:	mechanical stress
Observed In:	anterior crista kinocilium lateral crista kinocilium posterior crista kinocilium whole organism swimming behavior
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol