FIGURE

FIGURE 3

ID

ZDB-FIG-210708-88

Publication

Uehara et al., 2021 - Recurrent NFIA K125E substitution represents a loss-of-function allele: Sensitive in vitro and in vivo assays for nontruncating alleles

Other Figures

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FIGURE 3

Phenotypes of ectopic expression of NFIA gene in Drosophila. Ectopic expression of NFIA^WT (a) but not NFIA^K125E (b) during retinal development (GMR>NFIA^WT) caused severe neurodegeneration (rough eye phenotype). Ectopic expression of NFIA^WT (c and d) but not NFIA^K125E (e and f) under the control of the ey‐GAL4 driver caused antenna‐to‐leg transformation. Note that the ey gene is expressed in the eye‐antennal disc primordia and ubiquitously in the first instar larval disc (Quiring et al., 1994; Urbach & Technau, 2003) [Color figure can be viewed at wileyonlinelibrary.com]

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Am. J. Med. Genet. A