FIGURE

FIGURE 2

ID

ZDB-FIG-210708-87

Publication

Uehara et al., 2021 - Recurrent NFIA K125E substitution represents a loss-of-function allele: Sensitive in vitro and in vivo assays for nontruncating alleles

Other Figures

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FIGURE 2

Amino acid sequence alignment of the DNA-binding domains of human NFIA with its orthologs and paralogs. Sequences and domain definitions were obtained from UniProt (The UniProt Consortium, 2019). HspA: human NFIA (Q12857, residues 1–194); HspB: human NFIB (O00712, 1–195); HspC: human NFIC (P08651, 1–195); HspX: human NFIX (Q14938, 1–194); Mmu: mouse Nfia (Q02780, 24–217); Xtr: frog nfia (A0A6I8RQ42, 1–194); Dre: zebrafish nfia (F1R2R8, 1–193); Dme: fly NfI (Q86P06, 19–212); and Cel: nematode nfi-1 (Q09631, 44–237). The K125E mutation site is indicated by an arrow; 6th and 7th mutagenized sites in Armentero et al. (1994) are underlined

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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