FIGURE

FIGURE 3

ID

ZDB-FIG-210530-17

Publication

Gong et al., 2021 - Claudin h Is Essential for Hair Cell Morphogenesis and Auditory Function in Zebrafish

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FIGURE 3

Loss function of the claudin h caused the vestibular dysfunction and hearing defects. (A) The schematic diagram shows the rotatory trajectory of the larva during VOR. (B) The heads and eyes of control and claudin h morphants acquired during VOR test at extreme tilting positions. (C,D) The vestibular function of zebrafish larvae at 5 dpf is evaluated by vestibular head tilt response measurement (right and left eyes, respectively). (E) The schematic diagram shows the startle response testing equipment. (F) The swimming trajectory of the control and claudin h morphants. (G,H) Swimming distance and peak velocity of zebrafish larvae at 5 dpf that reflected the auditory function of zebrafish larvae by examining the startle response. Values with *, ***, and ****above the bars are significantly different (P < 0.05, P < 0.001, and P < 0.0001, respectively).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO4-cldn3c
Knockdown Reagent:	MO4-cldn3c
Observed In:	whole organism detection of mechanical stimulus involved in sensory perception of sound whole organism swimming behavior
Stage:	Day 5

Phenotype Detail

Acknowledgments

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