FIGURE

Fig. 2

ID

ZDB-FIG-210520-53

Publication

Mitchell et al., 2021 - The alx3 gene shapes the zebrafish neurocranium by regulating frontonasal neural crest cell differentiation timing

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Fig. 2

(A) Individual UMAP feature plots for the Alx transcription factor-encoding genes. alx1, alx3, alx4a and alx4b are enriched in the frontonasal NCC population relative to other populations. All individual feature plots have the same scale. (B) Violin plots illustrate relative Alx gene expression in the anterior arches (aa), frontonasal region (fn), posterior arches (pa) and melanocyte population (m). (C-E) In situ hybridization reveals where the alx3-expressing frontonasal population resides in intact embryos: alx3 is strongly expressed in NCCs residing between the eye and the nasal placode (np) (C), alx3-expressing cells are found medial to the nasal placodes (D) and alx3 is expressed in cells ventral to the nasal placodes (E). Scale bars: 50 µm.

Expression Data

Genes:	alx1 alx3 alx4a alx4b
Fish:	vu234Tg; y1Tg
Anatomical Terms:	chondrocranium cartilage neural crest cell olfactory placode
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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