FIGURE

Figure 1

ID

ZDB-FIG-201111-1

Publication

Zhang et al., 2020 - Suppression of Inflammation Delays Hair Cell Regeneration and Functional Recovery Following Lateral Line Damage in Zebrafish Larvae

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Figure 1

CuSO₄ damages hair cells in the lateral line of zebrafish. (A) Lateral line hair cells in a 6 days postfertilization (dpf) wild-type AB zebrafish larva is labeled with 0.05% DASPEI. L2, LII3, and L3 neuromasts are marked with circles. Scale bar represents 500 μm. (B) The lateral view of a neuromast shows sensory hair cells in the center labeled with DASPEI and a bundle of kinocilia (arrow) extending out of the periderm. Scale bar represents 10 μm. (C) A cartoon illustrates the structure of the neuromast. (D) Time lapse imaging shows that when immersed in 5 μM CuSO₄ solution, hair cells were gradually injured and damaged within 60 min. Scale bar represents 10 μm. (E) DASPEI staining displays that hair cells regenerate completely within 96 h postinjury (hpi). Scale bar represents 10 μm.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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