FIGURE

Fig 1

ID

ZDB-FIG-200724-10

Publication

Jiang et al., 2020 - Transcriptome analysis indicates dominant effects on ribosome and mitochondrial function of a premature termination codon mutation in the zebrafish gene psen2

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Fig 1

Predicted protein sequence of <italic>psen2</italic><sup><italic>S4Ter</italic></sup>.

(A) An 8-bp deletion resulted in a frameshift downstream of the nominal translation start codon of psen2 creating a stop codon as the 4^th codon. (B) Comparison of the epidermal pigmentation of adult, male zebrafish. Wild type (upper), psen2^S4Ter homozygous (middle), and psen2^N140fs homozygous (lower) zebrafish. The S4Ter mutation permits apparently normal melanotic epidermal pigmentation while the N140fs mutation does not.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	psen2^uaa7/uaa7 psen2^uaa11/uaa11 (TU)
Observed In:	melanophore stripe melanocyte
Stage:	Adult

Phenotype Detail

Acknowledgments

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