FIGURE

Fig 6

ID

ZDB-FIG-200412-19

Publication

Lee et al., 2020 - Chondroitin sulfate proteoglycan 4 regulates zebrafish body axis organization via Wnt/planar cell polarity pathway

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Fig 6

Cspg4 transmembrane domain mutant embryo phenocopied <italic>cspg4</italic> overexpression phenotype.

(A) Scheme illustrates wild-type and mutant Cspg4 protein structure. (B) The flag-tag signal of both wild-type and mutant Cspg4 were detected in the cell lysate, but in culture medium the signal of flag-tag was only detected in mutant Cspg4-flag transfected group. (C) Eight percent of cspg4^em1twu0405 embryos were cyclopia. (D) Four percent of cspg4^em1twu0405 embryos showed midline bifurcation (notochord was indicated by asterisk).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-cspg4 + MO2-cspg4
Knockdown Reagents:	MO1-cspg4 MO2-cspg4
Observed In:	axis eye notochord
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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