FIGURE

Fig. 4

ID

ZDB-FIG-190816-31

Publication

Fogerty et al., 2019 - Genomic non-redundancy of the mir-183/96/182 cluster and its requirement for hair cell maintenance

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Fig. 4

Survey of retinal anatomy in 5dpf mutant larvae. Transverse sections were collected near the optic nerve, which is visible in some images (asterisks), and stained with markers for different photoreceptor cell types. In all images, the ventral retina is to the left. (a) Peanut agglutinin lectin (PNA) labels the extracellular matrix surrounding cone outer segments. (b) zpr1 labels red/green cone inner segments. Inserts show higher magnification images, with double arrows indicating how inner segments were measured. (c) zpr3 labels rod outer segments, which are immature at this age and typically longer and more numerous in the ventral retina.

Expression Data

Antibodies:	zpr-1 zpr-3
Fish:	WT Df(Chr4:dre-mir-183,dre-mir-182)lri81/lri81 dre-mir-96^lri60/lri60 dre-mir-96^{lri79a/lri79a} dre-mir-182^lri61/lri61 dre-mir-183^lri70/lri70 Df(Chr4:dre-mir-96,dre-mir-183)lri69/lri69 Df(Chr4:dre-mir183,dre-mir096,dre-mir-182)lri78/lri78
Anatomical Terms:	retinal cone cell photoreceptor inner segment retinal rod cell rod photoreceptor outer segment
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	Df(Chr4:dre-mir-183,dre-mir-182)lri81/lri81 dre-mir-96^lri60/lri60 dre-mir-96^{lri79a/lri79a} dre-mir-182^lri61/lri61 dre-mir-183^lri70/lri70 Df(Chr4:dre-mir-96,dre-mir-183)lri69/lri69 Df(Chr4:dre-mir183,dre-mir096,dre-mir-182)lri78/lri78
Observed In:	retinal cone cell retinal cone cell photoreceptor inner segment retinal cone cell development retinal rod cell retinal rod cell development
Stage:	Day 5

Phenotype Detail

Acknowledgments

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