FIGURE
Fig. S4
- ID
- ZDB-FIG-190702-9
- Publication
- Lahrouchi et al., 2019 - Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly
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Fig. S4
Morpholino mediated knockdown of zebrafish fat1a causes coloboma Morpholino mediated knockdown of fat1a consistently resulted in coloboma at two different concentrations (a, b, d, f and h), whereas injection of similar amount of control morpholino did not cause coloboma (a, b, c, e and g). Fused optic fissure margins of zebrafish larvae (day 3 post fertilization) can be observed (e and g; sagittal section) after histology and toludene blue staining, whereas the fissure margins remained unfused in fat1a morphant embryos (f, and h). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Protruding-mouth |
Phenotype Detail
Acknowledgments
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Full text @ Nat. Commun.