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Fig. S4
Morpholino mediated knockdown of zebrafish fat1a causes coloboma Morpholino mediated knockdown of fat1a consistently resulted in coloboma at two different concentrations (a, b, d, f and h), whereas injection of similar amount of control morpholino did not cause coloboma (a, b, c, e and g). Fused optic fissure margins of zebrafish larvae (day 3 post fertilization) can be observed (e and g; sagittal section) after histology and toludene blue staining, whereas the fissure margins remained unfused in fat1a morphant embryos (f, and h).
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Full text @ Nat. Commun.