FIGURE

Fig. 6

ID

ZDB-FIG-190530-8

Publication

Bhakta et al., 2018 - pouC regulates expression of bmp4 during atrioventricular canal formation in zebrafish

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Fig. 6

pouC regulates myocardial specification in the AVC. A: Representative in situ hybridization analysis performed on control and pouC morphant zebrafish at 48 hpf. B: Same as in (A) at 72 hpf. C: Zebrafish embryos were injected with control or pouC MO, and in situ hybridization analysis was performed at 24 hpf using the indicated probes. D: Schematic summary of marker analysis, demonstrating a specific defect in AVC cardiomyocyte specification in pouCmorphant embryos. anf, atrial natriuretic factor; amhc, atrial myosin heavy chain; vmhc, ventricular myosin heavy chain. Cardiac borders outlined with dotted lines, and arrowheads indicate region of AVC.

Expression Data

Genes:	bmp4 myh6 myh7 notch1b nppa vcana
Fish:	AB AB + MO1-pou6f1
Knockdown Reagent:	MO1-pou6f1
Anatomical Terms:	atrioventricular canal atrioventricular canal myocardium atrioventricular canal endocardium atrium cardiac muscle cell cardiac ventricle cardiac muscle cell heart tube presumptive atrium heart tube cardiac muscle cell presumptive cardiac ventricle heart tube cardiac muscle cell
Stage Range:	Prim-5 to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-pou6f1
Knockdown Reagent:	MO1-pou6f1
Observed In:	atrial cardiac muscle cell development atrioventricular canal atrioventricular canal cardiac muscle cell development atrioventricular canal myocardium atrioventricular canal morphogenesis ventricular cardiac muscle cell development
Stage Range:	Prim-5 to Protruding-mouth

Phenotype Detail

Acknowledgments

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