Gene
vcana
- ID
- ZDB-GENE-011023-1
- Name
- versican a
- Symbol
- vcana Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity and hyaluronic acid binding activity. Involved in endocardial cushion morphogenesis; pronephric glomerulus morphogenesis; and regulation of glomerular filtration. Predicted to localize to extracellular matrix. Human ortholog(s) of this gene implicated in intracranial aneurysm. Is expressed in several structures, including anterior neural keel; mesoderm; otic vesicle; pericardial region; and semicircular canal. Orthologous to human VCAN (versican).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 64 figures from 48 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb63 (12 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Wagner syndrome 1 | 143200 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Conserved_site | IPR018378 | C-type lectin, conserved site |
| Domain | IPR000436 | Sushi/SCR/CCP domain |
| Domain | IPR000538 | Link domain |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001304 | C-type lectin-like |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Domain | IPR033987 | Aggrecan/versican, C-type lectin-like domain |
| Family | IPR050691 | Hyaluronan-binding Proteoglycan |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR016186 | C-type lectin-like/link domain superfamily |
| Homologous_superfamily | IPR016187 | C-type lectin fold |
| Homologous_superfamily | IPR035976 | Sushi/SCR/CCP superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Length | Aggrecan/versican, C-type lectin-like domain | C-type lectin, conserved site | C-type lectin fold | C-type lectin-like | C-type lectin-like/link domain superfamily | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Hyaluronan-binding Proteoglycan | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain | Link domain | Sushi/SCR/CCP domain | Sushi/SCR/CCP superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A2R8Q3K1
|
635 | ||||||||||||||||||
|
UniProtKB:A0A8M9PX21
|
8936 |
Interactions and Pathways
No data available
Plasmids
No data available