FIGURE

Fig. 6

ID

ZDB-FIG-181026-1

Publication

Fu et al., 2018 - Novel Animal Model of Crumbs-Dependent Progressive Retinal Degeneration That Targets Specific Cone Subtypes

Other Figures

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Fig. 6

Secreted Crb2b-sf^EX promotes RGB cone degeneration and rod overpopulation. (A) JB4-Feulgen histology illustrates nuclear morphologies and distributions of photoreceptors in the central area of WT and pt108b retinas at 15 mpf and 27 mpf. (B) Histograms of average linear densities of photoreceptors in central retina of WT and pt108b at 15 and 27 mpf. Mean ± 1 SD, n = 5. (C) Formula for the photoreceptor maintenance index. (D) In the central retina in pt108b, the photoreceptor maintenance indexes show loss of RGB cones, excess rods, and no effect on UV cones.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pt108bTg
Observed In:	green sensitive photoreceptor cell red sensitive photoreceptor cell retinal cone cell photoreceptor cell maintenance retinal rod cell retinal rod cell photoreceptor cell maintenance
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Invest. Ophthalmol. Vis. Sci.