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Fig. 6
Secreted Crb2b-sfEX promotes RGB cone degeneration and rod overpopulation. (A) JB4-Feulgen histology illustrates nuclear morphologies and distributions of photoreceptors in the central area of WT and pt108b retinas at 15 mpf and 27 mpf. (B) Histograms of average linear densities of photoreceptors in central retina of WT and pt108b at 15 and 27 mpf. Mean ± 1 SD, n = 5. (C) Formula for the photoreceptor maintenance index. (D) In the central retina in pt108b, the photoreceptor maintenance indexes show loss of RGB cones, excess rods, and no effect on UV cones.
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Full text @ Invest. Ophthalmol. Vis. Sci.