FIGURE

Fig. S2

ID

ZDB-FIG-180927-44

Publication

Karra et al., 2018 - Vegfaa instructs cardiac muscle hyperplasia in adult zebrafish

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Fig. S2

Transgenic overexpression of vegfaa from cardiomyocytes. (A) Transgenic approach to overexpress vegfaa from cardiomyocytes. (B-C) In situ hybridization for vegfaa on sections from ventricles of cmlc2:CreER; βact2:BS-vegfaa animals 7 days post incubation (dpi) with vehicle or tamoxifen. Violet staining indicates expression. Boxed region corresponds to the magnified region shown in the adjacent panels. (D-E) Schematic depicting juvenile and adult experiments in Figure 3. (F-G) Tile-scanned images of ventricular surfaces from cmlc2:CreER; βact2:BS-vegfaa; fli1a:EGFP fish at 6 wpf following incubation with vehicle or tamoxifen at 30 dpf. (H-I) Tile-scanned images of sections from ventricles of cmlc2:CreER; βact2:BS-vegfaa; fli1a:EGFP animals 7 days after treatment with vehicle or tamoxifen. Yellow arrows indicate nucleated blood cells in the lumen of ectopic blood vessels. (Scale bars 100 μm)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA