Fig. S1

Fraction of non-dividing, dividing and eliminated cell populations in wild-type, E-cadherin mutant and N-cadherin morphant lenses

(A) Histogram of mean percentages of non-dividing (ND, blue), dividing (DV, red) and eliminated (E, grey) cell populations in five wild-type, three E-cadherin mutant, and three N-cadherin morphant lenses at 33 hpf. The fraction of dividing cell population was lower in E-cadherin mutant than in wild-type and N-cadherin morphant lenses.

(B–D) Fractions of non-dividing (B), dividing (C) and eliminated (D) cell populations in the anterior lens epithelium of the wild type, the E-cadherin mutant and the N-cadherin morphant at 33 hpf. Values for five wild-type, three E-cadherin mutant and three N-cadherin morphant lenses are plotted. Means and standard deviations are indicated by horizontal bars and vertical lines, respectively. Probabilities are calculated using Student’s t-test: *p<0.05. In the case that probabilities are 0.05(E–G) Cell movement trajectory and displacement of additional four wild-type (E), two E-cadherin mutant (F), and two N-cadherin morphant lenses that we analyzed in this study. Scale bars: 10 μm.