FIGURE

Fig. 4

ID

ZDB-FIG-180627-4

Publication

Prabhudesai et al., 2018 - Cystathionine β-Synthase Is Necessary for Axis Development in Vivo.

Other Figures

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Fig. 4

cbsb morphant phenotype at 52 hpf. Low magnification images of 52 hpf Tg (flk:EGFP) embryos injected with 2 ng CBSB-S1 (A) and 2 ng control (Con) MO are shown. Panel (C) shows various phenotypes observed from mild to server for CBSB-S1 at 52 hpf. Note the progressive loss of axis length. Panel (D) shows quantification of the length of the axis is shown in (A). Y-axis shows mean length of the embryo measured as the longest horizontal dimension between the start of the yolk and the end of the tail (n = 11 for CBSB-S1 and ConMO-injected embryos), ****P < 0.0001. In the figure panels, the embryo orientation is left is anterior (A) and right is posterior (P) while top is dorsal (D) and bottom is ventral (V). Scale bars indicate 0.25 mm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-cbsb la116Tg + MO2-cbsb
Knockdown Reagent:	MO2-cbsb
Observed In:	vasculature whole organism anterior-posterior axis
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol