FIGURE

Fig. S8

ID

ZDB-FIG-180611-77

Publication

Freudenblum et al., 2018 - In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis.

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Fig. S8

Single cell plots of cell morphology time series. Related to Figure 5.

(A) Schematic illustration showing the impact of cell protrusions on the morphology parameter solidity. Broad protrusions (upper right, arrowhead) increase both cell and convex hull area. Narrow protrusions (lower right, arrowhead) increase convex hull area while minimally influencing cell area, thus more significantly impacting solidity as compared to broad protrusions. For cells treated and imaged as in Fig S8A, parameters of area (B), circularity (C), and solidity (D) plotted for each cell versus time (x-axis), under control (left), WORT treated (center), and Ly294002 treated (right) conditions.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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