FIGURE

Fig. 3

ID

ZDB-FIG-180131-29

Publication

Gong et al., 2017 - Insm1a Regulates Motor Neuron Development in Zebrafish

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Fig. 3

Insm1a deficiency suppressed neuronal cells differentiation. (A) Confocal imaging analysis of primary motor neuron in control group, insm1a mutant group and morphant group at 30 and 48 hpf Tg(mnx1:GFP)^ml2. Phenotypes of neuronal cells in the spinal cord in control group, morphant group, and insm1a mutant groups at 30 hpf and 48 hpf. Asterisks indicate undifferentiated neuronal cells. Scale bar = 50 μm. (B) Quantification of the undifferentiated neuronal cell in the insm1a different treatment zebrafish. Asterisks above the bars indicate significant differences (*P < 0.05, **P < 0.01). (C) Time-lapse imaging analysis of the primary motor neuron in control group and insm1a mutant groups. Asterisks represent undifferentiated neuronal cells. Scale bar = 50 μm

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ml2Tg + CRISPR1-insm1a ml2Tg + MO5-insm1a
Knockdown Reagents:	CRISPR1-insm1a MO5-insm1a
Observed In:	neuron neuron differentiation
Stage Range:	Prim-15 to Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.