FIGURE

Fig. S10

ID

ZDB-FIG-170907-45

Publication

Gerri et al., 2017 - Hif-1α regulates macrophage-endothelial interactions during blood vessel development in zebrafish

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Fig. S10

Repaired blood vessels in WT embryos regain blood flow.

(a) Maximal intensity projections of confocal z-stacks of a blood vessel rupture in a 54 hpf Tg(kdrl:EGFP);Tg(gata1:DsRed) WT embryo after DMOG treatment for 6 hours starting at 48 hpf. (b) Maximal intensity projections of confocal z-stacks of the same blood vessel in the same embryo after repair. Lateral views; white arrow points to a ruptured vessel showing erythrocyte leakage, white arrowhead points to repaired vessel having regained flow. (c) Quantification of ruptured vessels subsequently repaired and showing presence (w/) or absence (w/o) of flow as well as those not repaired; data collected at 75 hpf. Bars represent mean ± s.e.m., n = 6 from 3 different clutches. (*P < 0.05; **P < 0.01; t-test). Scale bar, 50 μm.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.