FIGURE
Fig. S3
- ID
- ZDB-FIG-170201-21
- Publication
- Liu et al., 2016 - The Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53
- Other Figures
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Fig. S3
Ataxin-3 expression-induced cell death occurs in cells and in HuC positive brain regions in zebrafish. (A) Flow cytometry analysis using Annexin V-FITC/PI staining in HCT116 p53+/+ cells. (B and C) Dorsal views with anterior to the top of Tg(HuC:EGFP) embryos. Colocalization of HuC:EGFP (green) and TUNEL positive foci (red) in the telencephalon region (B) and diencephalon/hindbrain (C). Tg(HuC:EGFP) transgenic embryos uninjected control (UIC) or injected with ataxin-3 were collected for TUNEL staining at 24 hpf. Scale bars, 20 μm for B and 50 μm for C. |
Expression Data
| Gene: | |
|---|---|
| Fish: | |
| Anatomical Terms: | |
| Stage: | Prim-5 |
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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