FIGURE
Fig. 2
- ID
- ZDB-FIG-161027-2
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- Huang et al., 2016 - Sox9b is a mediator of retinoic acid signaling restricting endocrine progenitor differentiation
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Fig. 2
RA and Notch signaling have separate effects on CAC differentiation. (A-D) Images of 5 dpf cftr:cftr-gfp dissected foregut following drug treatment. GFP signal is abolished in larvae treated with DAPT (C) and RA+DAPT (D). (E-H) Images of anti-2F11 staining in 5 dpf dissected foregut following drug treatment. Expression of the ductal epithelial marker 2F11 is maintained under all treatment conditions. Larvae were incubated from 3 to 5 dpf with DMSO (A, E), RA (B, F), DAPT (C, G), or RA+DAPT (D, H). White dashed lines outline pancreata. Scale bar=100 µm. |
Expression Data
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| Stage: | Day 5 |
Expression Detail
Antibody Labeling
Phenotype Data
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| Stage: | Day 5 |
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 418(1), Huang, W., Beer, R.L., Delaspre, F., Wang, G., Edelman, H.E., Park, H., Azuma, M., Parsons, M.J., Sox9b is a mediator of retinoic acid signaling restricting endocrine progenitor differentiation, 28-39, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.